Hi Jimr,
Thank you for using the Support Forum. If you have already done all those things that are recommended in the article Unable to Perform TWAIN Scan When USB Connected to Windows 10 and it sounds like you have then please consider contacting your support centre for further assistance.
I have a new lenovo thinkpad, I have a xerox workcenteer3215, I have downloaded the drivers and packages, the printer will print on usb hook up (cannot get the wifi to connect!) but it will not scan, on easy document creator the bottom left keeps spinning as if it cannot find the printer, though it will becasue it does print, I have downloaded everythng from xerox including a patch 3215_win10_rs4_patch_220618. NOTHING works!