Thank you for using the Support Forum. Have you tried one of the color profiles found here? For the spots please take a look at this article on Repeating Marks and Spots. Please consider contacting your support centre for further assistance.
This is how the colors are coming out. The top photo is how it turns out once we print. The bottom photo is the color when on the computer before printing. We have had the Cyan drum replaced twice, and the toners are all full as well. Please help!