Find out where the problem comes from.
Print from the print option in Acrobat (testing the driver and app)
Print from Acrobat with "print as image" selected (testing the driver and removing transparencies and fonts etc etc)
Import the pdf direct via Webtools or CWS (Eliminates the software and the driver)
If it happens with import, either the file is terribly made and spools to 2GB or more and crashes the system, or the Fiery is corrupt/has bad HDD/RAM
If the driver is the problem, make sure you use a LPR port and that SNMP and LPR Byte counting is not enabled on it, then try another driver if still an issue.
If the issue lies in Acrobat, either change the settings (print as image, font policy etc etc) or start creating files for print properly ala PDF/x to strip out the garbage data (transparencies/layers etc)
We have noticed that when we need to print a pdf file that is 360MB in file size and 400 pages big will crash the Fiery and printer at the same time. Sometimes even couple 100MB files with 120 or so pages will freeze the printer which requires a reboot. What can be done to address this issue?